American Science Cloud

Accelerating innovation with AI and advanced computing

The American Science Cloud (AmSC) is a cornerstone of the Genesis Mission’s platform—an integrated, federated platform that connects AI models, curated scientific data, workflows, and computing resources across DOE laboratories to accelerate discovery, enable autonomous science, and scale impact to the broader research ecosystem.

What is AmSC?

A Platform for Transformative Science

AmSC is a secure, federated, and science-optimized cloud environment that integrates the DOE’s world-leading computing and experimental facilities, data resources, and high-performance networks.

AmSC enables DOE scientists to create, access, and integrate world-class AI-ready datasets, run scalable model training on leadership-class systems, perform distributed simulations, control instruments, and move data efficiently across sites.

Infrastructure Partners
What will AmSC provide?

Advanced AI Tools for Scientific Discovery

AmSC provides core platform services designed to make DOE data and compute usable at mission scale—securely and consistently across partners.

Data Services

Ensure DOE’s vital data assets are FAIR and AI-ready.

Model Services

Enable access to state-of-the-art models for scientific discovery.

AI Services

Harness leadership-class systems for extreme-scale model training and inference.

Infrastructure Services

Provide secure, uniform access to compute, storage, and networking across DOE and cloud partners.

What Will AmSC Achieve?

A New Era of Interconnected Research

As a foundational pillar of the Genesis Mission, AmSC establishes a durable, extensible platform designed to help transform the scientific method—embedding AI and advanced computing directly into the full lifecycle of discovery.

By combining intuitive interfaces, scalable services, and DOE’s unparalleled scientific assets, AmSC integrates models, data, workflows, and compute into a unified environment that enables faster hypothesis generation, experimentation, and insight.

Once deployed, the AmSC Platform will power Genesis mission use cases, deliver core API-driven services, and demonstrate seamless interoperability across facilities and partners—laying the groundwork for autonomous, AI-driven science at scale.

Public-Private Partnerships Framework

Co-design, Validate, and Scale Together

AmSC creates a practical pathway for industry and the DOE ecosystem to co-design, validate, and operationalize capabilities that meet extreme-scale scientific and national security workloads—while expanding durable partnerships.

Technology Validation

Cloud service providers and vendors validate technologies against extreme-scale scientific and national security workloads, co-design solutions with DOE researchers, and evolve pilots into sustainable offerings.

Long-term Partnerships

Participation strengthens long-term relationships with DOE and expands opportunities for innovation. Secure data access in CSP environments creates new avenues for industry and the public to leverage scientific data.

Strategic Computing Reserve

AmSC charts a path toward a National Strategic Computing and AI Reserve—supporting steady-state research and surge capacity in times of crisis to ensure resilience and U.S. competitiveness.

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The Latest from AmSC

News, events, and resources including slides, Q&A, and recordings added after each event

Events & Resources
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